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The word is now commonly used as an incantation by magicians. In ancient times, however, it was taken much more seriously as an incantation to be used as a cure against fevers and inflammations. The first known mention was in De Medicina Praecepta by Serenus Sammonicus, physician to the Roman emperor Caracalla, who prescribed that the sufferer from the disease wear an amulet containing the word written in the form of an inverted cone:
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